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Similar to many residues in the primary chain of SOD1, Cys111 11 is proximal to the dimer interface and, not surprisingly, the introduction of GSH has been proposed to augment dissociation 11

Developmental and adult phenotyping directly from mutant embryonic stem cells

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GSH is a major determinant of the Reduction Oxidation Potential in the cell and is protectively involved in diverse cell activities, including control of cell cycle progression in human natural killer cells, and defensive responses to infections, to chemical exposures, and to other detrimental factors such as diesel exhaust particles, aging, diabetes, and photo-oxi dative retinal damage