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A role of the Duffy antigen for the maintenance of plasma chemokine concentrations

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For ease of study in the laboratory, the stress responses are often provoked by the external addition of chemical oxidants that specifically elevate the levels of reactive oxygen species within cells, or by the use of mutant strains that disrupt the normal homeostatic mechanisms for removing reactive oxygen species or the damage they do

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Tumors can also utilize myeloid plasticity to directly manipulate dendritic cell differentiation, skewing it toward immune-suppressive macrophage-like subsets that correlate negatively with the immune response to anti-PD-L1 and anti-CTLA-4 therapies [106]

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The differential antioxidant responses are particularly noteworthy

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In: Odin P, Chaudhuri KR, Aquilonious SM, et al., editors

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Gheissari A, Aslani N, Eshraghi A, et al

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