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Karimian, A

Nevertheless, an extended period of elevated glucose levels, as shown in diabetes mellitus (DM), can have a negative impact on the hypothalamus-pituitary-testis axis (HPT axis), resulting in reduced secretion of gonadotropins and the production of total testosterone (TT), combined with impaired functioning of endothelial cells

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To test this hypothesis, DEX, a potent anti-inflammatory drug, was utilized as the model hydrophobic payload