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The ERK and Akt signaling pathways in recipient cells are activated by pEXOs therapy

This gene expression profile, along with the smaller visceral adipocyte size, is consistent with healthy visceral WAT remodelling during HFD feeding in NDI1-expressing mice

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12.5%, P=0.0786)

Understanding these mechanisms broadens the understanding of the consequences of pigmentation disorders but also paves the way for innovative therapeutic approaches aimed at reducing oxidative stress in melanocytes