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CF and YY participated in revising the manuscript

PRESERVA LA HIDRATACIN: Infundido con cido hialurnico y beta glucano

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Preferred sites: Abdomen (avoid 2 inches around navel) Front or outer thigh Upper arm (posterior) Technique: Clean injection site with alcohol swab Let alcohol dry completely Pinch fold of skin Insert needle at 45-90 degree angle Inject slowly over 5-10 seconds Release skin, withdraw needle Light pressure if any bleeding Rotate sites to prevent tissue irritation

Hassanin HA, Koko M, Abdalla M, Mu W, Jiang B

In subjects with ACS and CAD, HDL have been reported to have decreased ability to prevent endothelial cell apoptosis likely through decreased activation (phosphorylation) of Bcl-xl and increased activation of Bcl-2, which are anti-apoptotic and pro-apoptotic proteins, respectively (840)