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Analysis of recombinant TNR (rTNR) Western blots For each blot, the fluorescence intensity of the bands was determined by manually selecting a rectangular ROI surrounding the band and correcting for local background (see 77 )

FIGURE 3 5 Mechanistic differences of ferroptosis in normal and cancerous tissues Ferroptosis, an iron-dependent lipid peroxidation-driven form of cell death, exhibits significant differences in its mechanisms between normal and cancerous tissues ( In normal tissues, ferroptosis is typically associated with cellular stress responses, antioxidant defense mechanisms, and immune regulation