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Persistent neurological symptoms, abnormal blood test results, or changes in health status warrant medical review and potential dose adjustment

It was designed to preserve growth hormones fat-metabolism effects while avoiding many of the growth-promoting and glucose-worsening issues associated with full-length hGH

It enrolled adults with a body mass index of 30 or greater, or 27 or greater with at least one weight-related comorbidity, and randomized them across multiple retatrutide dose arms (1 mg, 4 mg, 8 mg, and 12 mg weekly) versus placebo