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Nanopolymers are broadly applied for the design of sustained release and site-specific drug delivery, resulting in improved therapeutic efficacy with fewer side effects (206, 227)

J Adv Pharm Technol Res 10:132

Oral bersteigt die Plasmakonzentration in der Praxis etwa 220 mol/l nicht, unabhngig von der Dosis, whrend eine Infusion von 50 g Werte in der Grenordnung von 13.400 mol/l erreichen kann, dreiig- bis siebzigmal hher (PMID 15068981)

But it must be interpreted with caution: without a control arm, we cannot exclude that this profile simply marks patients who would have improved with optimal standard care alone