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[DOI] [PubMed] [Google Scholar] 79.Lucarelli G., Galimberti M., Polchi P., Angelucci E., Baronciani D., Durazzi S.M

Indeed, the stronger relationship between elevated circulating homocysteine levels and atherothrombotic disease observed in retrospective case-controlled studies than in prospective studies might be explained by the younger average age of subjects sustaining a coronary event in retrospective studies (in the positive study by Wald et al (1998), see the age comparison between retrospective and prospective studies)