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Improved blood flow enhances oxygen and nutrient delivery, which is essential for sustaining active growth during the anagen phase

The trial enrolled 281 participants across 42 research and healthcare centers in the United States, randomized to once-weekly subcutaneous retatrutide (0.5, 4, 8, or 12 mg), once-weekly subcutaneous dulaglutide 1.5 mg (active comparator), or placebo, over a 36-week treatment period

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Third, although we focused exclusively on female patients in line with the epidemiology of lipedema, future studies should consider potential sex-specific differences and include appropriate controls for hormonal status, menopausal state, and body mass index (BMI)

people under 18 should talk to a doctor first

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