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Hwang C, Sinskey AJ, Lodish HF

Pharmacogenomics 15, 941950

Parakh et al., 2018a) cellular models (Farg et al., 2012

Achan J, Talisuna AO, Erhart A, Yeka A, Tibenderana JK, et al

Melhem JM, Detsky J, Lim-Fat MJ, Perry JR

Interestingly, in xenograft model, Polyphyllin III, a major saponin extracted from Paris polyphylla rhizomes, which induces Kruppel Like Factor 4-mediated protective upregulation of SLC7A11, in combination with the System X c inhibitor SAS, may have a co-induction in MDA-MB-231 breast cancer cells by enhancing intracellular lipid peroxidation and ferroptosis (Zhou Y