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J Nutr Biochem 2015, 26 (9), 921928

Sandwich ELISA The recommended antibody orientation is based on internal optimization for ELISA-based assays

Response: We thank the commenter for this recommendation and refer the commenter to the policies set forth in 428.301, 428.302, and 428.303 and discussed later in this final rule regarding rebate reductions for certain Part D rebatable drugs currently in shortage, likely to be in shortage, or experiencing a severe supply chain disruption, as authorized under section 1860D-14B of the Act

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Toxicology workup as indicated (e.g., salicylate level, urine toxicology screen including cocaine and methamphetamine)

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