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doi: 10.1002/mnfr.201600274 65

Lack of MDA5 delays hematopoietic aging by modulating inflammaging and proteostasis in mice

Bulletin of Experimental Biology and Medicine, 133 , 614-616

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In summary, methionine restriction selectively exacerbates the oxidative stress in cancer cells by targeting their antioxidant metabolic vulnerability-particularly through disrupting glutathione synthesis-thereby ultimately inducing cell death