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It is widely recognized that prolonged exposure to elevated levels of ROS can lead to oxidative DNA damage associated with a COSMIC (catalog of somatic mutations in cancer) mutation signature (Rose et al

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Chem Biol Interact 365:110111

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Clemente-Surez VJ, Ramos-Campo DJ, Mielgo-Ayuso J, Dalamitros AA, Nikolaidis PA, Hormeo-Holgado A, Tornero-Aguilera JF (2021) Nutrition in the actual COVID-19 pandemic

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Overview of all the structural information available in the PDB for UniProt: P50213 (Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial) at the PDBe-KB

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