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10.1111/j.1365-2567.2007.02687.x 55

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Although very rare, severe allergic reactions like anaphylaxis (sudden blood pressure drop, difficulty breathing, facial swelling), toxic epidermal necrolysis, and Stevens-Johnson syndrome (high fever, severe skin and mucous membrane damage) have been reported, but they are not more frequent than with other medications

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For IHC analysis, gut pathology was additionally included as an interaction term because of previous studies showing association between gut pathology and these outcomes (Sun et al., 2018)