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Kanazawa LK, Vecchia DD, Wendler EM, Hocayen PAS, Dos Reis Lvero FA, Stipp MC, et al

In fulfilling this protective role, reduced glutathione is converted into oxidized glutathione, at which point it becomes inactive

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They proposed that MMP9 induced peritoneal angiogenesis by cleaving E-cadherin and activating b-catenin signaling, which increased VEGF expression (Padwal et al., 2017)

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On the other hand, bone- and lung-specific metastases divert pyruvate flux into mitochondrial oxidative metabolism to promote metastasis