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Activated BCL2-interacting protein 3 (BNIP3)-dependent and PTEN-induced putative kinase1 (PINK1)-Parkin pathway-mediated mitophagy were detected in microglia of IH model, the former was activated by c-Jun N-terminal kinase (JNK)-extracellular regulated kinase (ERK) signaling pathway and the latter was regulated by nucleotidebinding domain like receptor protein 3 (NLRP3) expression [63, 64]

Kantarjian H, OBrien S, Beran M, Keating M, Koller C, Robertson L, Andreeff M , Murphy S, Freireich E

Jiang Y, Sun A, Zhao Y, Ying W, Sun H, Yang X, et al

I., Kearney, J., Knutsen, H

Microglia play an active role in obesity-associated cognitive decline

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