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LfcinB(2025)4 also exploits membrane permeability, causing severe damage and generating the effect of necrosis on tumor cells [21]

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Although positive changes to these risk factors can reduce disease severity in patients, it is not a silver bullet and HS is still found in patients who are non-smokers, and in those of a healthy weight 4

It is modulated by isocitrate dehydrogenase (IDH) mutation status, which showing marked upregulation in IDH-wildtype tumors (Rocha et al., 2025)

[149] used an artificial miRNA to silence the cucumber mosaic virus (CMV) suppressor 2b sequence utilizing an A

It enhances antioxidant enzyme activity, including superoxide dismutase and catalase