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This observation suggests that metabolic dysregulation in SLE extends to the memory B cell compartment and may contribute to persistent autoimmune responses

doi: 10.1016/j.cell.2025.08.015

(2017) The effect of N-acetylcysteine on exacerbations of chronic obstructive pulmonary disease: a meta-analysis and systematic review

There are two main pathways for cysteine catabolism: one is via its enzymatic breakdown to produce H 2 S and organic intermediates that will serve as carbon sources, and the second is via oxidative metabolism through cysteine dioxygenase (CDO)