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Lysine also acts as a precursor for carnitine, which is involved in fatty acid -oxidation, and its metabolic intermediate, -aminoadipic acid, serves as a precursor for certain secondary metabolites

The inactivation of Dnmt3a and Dnmt3b during early embryonic development hindered de novo methylation (Feng et al., 2010)

However, in pregnancies with high blood sugar levels (such as those with GDM), the placenta's development can be affected, leading to various complications such as increased oxidative stress, fetal thrombosis, maternal vascular malperfusion, and an imbalance in vasoactive molecules

Throughout the reproductive lifespan, women typically undergo over 400 cycles of endometrial regeneration, differentiation, and shedding (Lv et al., 2018)