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N Engl J Med 343(13):923930 Seikaly MG, Salhab N, Gipson D, Yiu V, Stablein D (2006) Stature in children with chronic kidney disease: analysis of NAPRTCS database

Moreover, studies have identified IDRs as enriched in the alternatively spliced protein segments, indicating that protein isoforms may display functional diversity due to the alteration of tissue-specific and species-specific modules within these regions 20

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After Insr gene expression was silenced by siRNA, the protein content of the IR-treated BMECs was quantified via western blotting