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While preclinical studies show promise, existing clinical evidence primarily comes from small-scale trials with methodological limitations

In the critically ill, vitamin C administered intravenously may help in the management of sepsis

Due to time and cost constraints, the number of clinical samples collected from the patients in both groups was limited

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A small superficial structureactivity analysis reflects that the location of the 2-benzothiazol at the 3-position of the benzylic-amine is preferred over the location at the 4-position in order to decrease the cytotoxic effect and achieve a higher SI

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