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Description

The first ubiquitin at the proximal end of the chain cannot bind to UT3 cleft, thus cannot serve as the initiator

& Renehan, A

Biotechnol Res Int 2012:243217

Duong HQ, You KS, Oh S, Kwak SJ, Seong YS

Its cellular regulation is tightly controlled by zinc transporters, particularly the Zip (Zrt/Irt-like protein) family (Zip1-14/SLC39 A1-14), which facilitates zinc influx into the cytoplasm, and the ZnT (Zinc Transporter) family (ZnT1-10/SLC30 A1-10), which mediates zinc efflux to maintain homeostasis