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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

Gao, L., Mejas, R., Echevarra, M

The way it works is worth understanding

SeaHorse-extracellular flux analyzer Cell Respiratory Assay OCR and ECAR were measured using the XFp extracellular flux analyzer (Seahorse Biosciences, now Agilent Technologies) as described by the manufacturer

GS, differently from GCL, is not feedback-inhibited by GSH and it is not associated with a regulatory subunit

10.1016/j.molcel.2016.02.011 Summary Keywords cell death, PCD, cancer, mechanism, therapy Citation Qi K, Mu Y, Hu Y, Li J and Liu J (2025) Comprehensive landscape of cell death mechanisms: from molecular cross-talk to therapeutic innovation in oncology