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& Layne, M

Mehta, S

But if you really look at the true cost of bringing a drug to market, it's still at minimal 300 million to a billion dollars to bring a drug or a, any sort of technology into the marketplace

Consequently, dose optimisation for nose-to-brain delivery involves a balance between achieving a therapeutic concentration at the target site with minimal nasal irritation (Chung et al., 2023