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The key organs that support detoxification pathways include the liver, kidneys, and skin, as well as the respiratory (lungs), lymphatic, and digestive systems

General mitochondrial function was assessed based on the Seahorse XF Cell Mito Stress Test protocol (Agilent Technologies, Santa Clara, CA, USA)

ROS can damage cellular components such as lipids, proteins, and DNA, leading to cell death and loss of cardiac contractile function

The advantages of batch purification are: 1) less time is required to perform the purification

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That said, a significant die-off reaction can also be a signal that detoxification pathways need more supportmore on this below