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Compared to serum, higher concentrations of individual compounds were observed in other specimens, such as blood cells, endothelial cells, synovial fluid and saliva, indicating pronounced distribution processes in vivo (see section 5 Biodistribution)

When the MDCK permeability values were examined, oleocanthal: -4.691, oleacein: -4.659, luteolin: -4.799, tyrosol: -4.689, ezetimibe: -4.722 and bempedoic acid: -4.764 were determined

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Won JH, Garcia-Sanchez F, Nanakorn T, Krause D, Pizzorno G, Wang WL, Liang J, Andreeff M , Zelterman D, Lin D, Srimatkandada S, Carbone R, Brown R, Deisseroth A

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HBOT-induced ROS generation may initiate adaptive signaling pathways that promote angiogenesis, tissue repair, and cellular survival, whereas excessive ROS accumulation contributes to oxidative damage and impaired microcirculation