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Eur Med J Fevrier-Paul A, Soyibo AK, De Silva N, Mitchell S, Nwokocha C, Voutchkov M (2021b) Addressing the challenge of potentially hazardous elements in the reduction of hypertension, diabetes and chronic kidney disease in the Caribbean

Additional information Communicated by Andre Wilke

Finally, we previously used an animal experiment to show that RGC loss in Nrf2 knockout mice was much faster after optic nerve damage was induced by crushing the nerve 41

Clinical research, such as a study evaluating heavy metal excretion, has demonstrated that NAC can actively pull toxic metals like lead, cadmium, and gold out of the blood and tissues, accelerating their clearance through the urine

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Furthermore, polar interactions among residues E200, S204, and N207 of mVP35d, and residues R774, Q325, T795, and K328 of MARL further enhance the structural stability of the NTP entry channel (Fig