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Studying potential adjunctive treatments targeting inflammation, Fabry patient-derived PBMCs showed significantly reduced secretion of pro-inflammatory cytokines upon in vitro treatment with pentosan polysulfate (PPS), although the action mechanism is not clear [47]

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PubMed Oberlick EM, Rees MG, Seashore-Ludlow B, Vazquez F, Nelson GM, Dharia NV, Weir BA, Tsherniak A, Ghandi M, Krill-Burger JM, Meyers RM, Wang X, Montgomery P, Root DE, Bieber JM, Radko S, Cheah JH, Hon CS, Shamji AF, Clemons PA, Park PJ, Dyer MA, Golub TR, Stegmaier K, Hahn WC, Stewart EA, Schreiber SL, Roberts CWM

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