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Peroxidation of the LDL subfraction may contribute to severe and premature cardiovascular diseases in patients with SLE

10.1016/S0140-6736(14)61909-7 15

The effects of age on the innate immune response include a decrease in pathogen recognition, chemotaxis, and phagocytosis, and in adaptive immunity, a decrease in the number of virgin T-lymphocytes and reduced cytotoxicity, as well as in the quality and quantity of antibodies [26]