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Dispone inoltre di una solida base di ricerca, con lavori che analizzano come inneschi la segnalazione del recettore dei secretagoghi dell'ormone della crescita (Raun et al., 1998, European Journal of Endocrinology)

doi: 10.1016/j.cell.2013.12.010 48 YaoX.ZhangY.HaoJ.DuanH

Originating from the cholesterol molecule, various biochemical transformations lead divergently to a large number of end products, which exert their actions via nuclear receptors and in some cases via receptors on cell membranes

DongPDMunsonCANortonWCrosnierCPanXGongZet al

This review introduces the common strategies of mitochondrial targeting, focuses on the targeting role and overall efficacy of mitochondria-targeted nanoparticles in CIRI models and finally analyses the advantages and potential shortcomings of this therapeutic strategy in CIRI

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