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Although they cannot develop Peyronies as quickly as men with the symptoms mentioned above, males with a congenital curvature can be also categorized as a subpopulation of men who are predisposed to the disease

Impaired activity of mitogen-activated protein kinase (MAPK) could result in possible immunosuppression

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Ethics declarations Ethics approval and consent to participate Manuscripts reporting studies involving human participants, human data, or human tissue must: The procedures and data collections in human study have been approved by Institutional Review Board of National Taiwan University Hospital (201507055MINC, 201712030RIND), and all participants signed a written informed consent form