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Holistic Approach: Takes a comprehensive approach to assess overall nutritional status, considering various factors that may influence nutrient metabolism and utilization

N Engl J Med (2013) 368:23458

Recent evidence suggests that aberrant brain-gut pathways, mitochondrial enzymopathies, gastrointestinal motility disorders, calcium channel abnormalities, and hyperactivity of the hypothalamic-pituitary-adrenal axis in response to a triggering environmental stimulus are involved

Complete resolution of sickle cell chronic pain with high dose vitamin D therapy: a case report and review of the literature

Further, fornix pathology is involved early in schizophrenia, 42, 43 although it is not known whether it is already affected in at-risk patients

Xie W, Su F, Wang G, Peng Z, Xu Y, Zhang Y, Xu N, Hou K, Hu Z, Chen Y, et al