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Glucagon-like peptide-1 (GLP-1)-based therapies, such as semaglutide and tirzepatide, have transformed obesity management, producing weight loss that narrows the gap with metabolic surgery at the same time as reducing the risk of obesity-related complications [2]

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The third possible mechanism through which the extract or phytochemicals interact with the inhibitory pathway is the targeting of GABA-T

doi: 10.2174/0929867330666221202152540

Higher resistance indicates reduced permeability, while lower resistance is associated with impaired permeability