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Furthermore, in a larger randomized, double-blind, placebo-controlled trial of selenium supplementation in 197 participants with asthma, 100 mcg of selenium per day for a treatment period of 24 weeks increased plasma selenium concentrations but failed to improve quality of life or other secondary measures of lung function, airway hyperreactivity, and symptoms when compared to the placebo-treated group (291)

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In other words, the agents can keep accommodative amplitude "above the line" (the solid line mean accommodative amplitude) depicted inFig

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