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The primary reasons people become deficient usually fall into two categories: Dietary Factors: Since B12 is mainly found in animal products (meat, fish, dairy, eggs), vegans and strict vegetarians are particularly susceptible if they dont consume fortified foods or specific supplements

J Neurosci 28:50075017

Routine rechecking of serum B12 levels is not generally recommended for patients on regular injections as levels will be artificially high

In younger patients, intra-axial lesions due to MS are more frequent

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While vitamin B12 plays a well established role in supporting metabolism and red blood cell formation, the benefits for energy and cognitive function in individuals without B12 deficiency have not been established in clinical studies