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Apart from ER stress, liver-specific overexpression of NACHT, Leucine-rich-repeat and pyrin domain-containing protein 3 (NLRP3) induced marked HSC activation and fibrosis, indicating a possible role of inflammatory cell death in inducing HSC activation (Wree et al., 2014)

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According to FAO/WHO, Probiotics are live non-pathogenic microorganisms, which when administered in adequate amounts, confer a health benefit on the host (161, 162)

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