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The ZUMA-1 study was a single-arm, phase III, multicenter trial of axicabtagene ciloleucel for patients with refractory large B cell lymphoma (11, 12)

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The process needs to perceive and integrate all kinds of signaling molecules, such as Ca 2+ , ROS, NO, H 2 S, and plant hormones, eventually forming a sophisticated signaling network controlling pollen germination and pollen tube growth ( In general, Ca 2+ plays a central role in pollen germination and pollen tube growth, and an increase in cytosolic free calcium concentration ([Ca 2+ ]cyt) is a fundamental signaling transduction event ( 2+ gradient (signaling) in pollen germination and pollen tube growth is not completely clear

NeuroRx 2(3):484494

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This dual activity plays a critical role in inhibiting NF-B activity, suppressing mitogen-activated protein kinase (MAPK) activation, and downregulating NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation ( ) were elevated, consistent with inadequate suppression of inflammatory signalling