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J Surg Oncol 131(5):793-803, 2025

In hepatic stellate cells (HSCs) adiponectin inhibits leptin-stimulated JAK2/STAT3 signaling and reduces TIMP-1 expression, through activation of AMP-activated protein kinase (AMPK) and induction of suppressor of cytokine signaling-3 (SOCS-3) [178]