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10.1111/j.1469-8137.1974.tb02151.x New Phytol

P., Schenke, W

465,466 Nevertheless, CRS and ICANS have emerged as significant obstacles impeding the broader application of CAR-T cell therapy in cancer treatment, marked by hyperactivation of the immune system and elevated levels of serum cytokines and pro-inflammatory molecules linked to the proliferation of CAR-T cells (Table 5)