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Genetics of amyotrophic lateral sclerosis: seeking therapeutic targets in the era of gene therapy

The role of the immune system in posttraumatic stress disorder

Additionally, Glutathione is recognized for its role in supporting the immune system and enhancing the bodys detoxification processes

Abbreviations 7nAChRs: Alpha-7-nicotinic acetylcholine receptors A: Amyloid- AD: Alzheimers disease ASD: Autism spectrum disorder ACh: Acetylcholine Akt: Protein kinase-B Bax: Bcl-2-associated X protein Bcl-2: B-cell lymphoma-2 CNS: Central nervous system DhE: Dihydro--erythroidine GABA: Gamma-aminobutyric acid GSH: Glutathione GPX: Glutathione peroxidase Hg: Mercury IL-1: Interleukin-1 MDA: Malondialdehyde MLA: Methyllycaconitine NF-B: Nuclear factor kappa B Nfr2: Nuclear factor erythroid 2related factor 2 NO: Nitric oxide NDDs: Neurodevelopmental disorders NMDA: N -methyl-D-aspartate PI3K: Phosphoinositide 3-kinases PV: Parvalbumin ROS: Reactive oxygen species TNF-: Tumor necrosis factor-alpha WHO: World Health Organization References Hodges H, Fealko C, Soares N (2019) Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation

Neuroinflammation or fever is presumed to also trigger ISR, as autoantibodies may target neural or immune systems and cause inflammation elsewhere (418)

Studies show its possible to raise glutathione