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Some newer growth hormone therapies can also indirectly raise IGF-1, but these medications are generally reserved for diagnosed endocrine disorders, as experts remain cautious about the potential risks of chronically elevated IGF-1, including a possible increased risk of cancer and other complications

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[DOI] [PubMed] [Google Scholar] Ritchie N.D., Ritchie R., Bayes H.K., Mitchell T.J., Evans T.J

Real-world US health records show the clinical uptake: the percentage of women with PMOS receiving at least one GLP-1 prescription rose from approximately 2% in 2021 to nearly 18% by 2025

J Biol Chem 274(12):76197622 Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions