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Additionally, adherence to such a restrictive dietary regimen poses a major challenge, highlighting the need for practical strategies to make KD more accessible and sustainable for patients

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However, without simultaneous reduction of obesity, the remarkable resistance to developing steatosis in hepatocyte Cul3-deficient mice paradoxically caused profound systemic insulin resistance

[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Proietti R., AlTurki A., Vio R., Licchelli L., Rivezzi F., Marafi M., Russo V., Potpara T.S., Kalman J.M., de Villers-Sidani E., et al

The accumulation of extracellular Amyloid Beta misfolding causes intracellular deposition of tau protein, leading to cognitive impairment