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Furthermore, alternative modes of tumor vascularization, such as intussusception, vasculogenic mimicry, transdifferentiation of cancer stem cells into endothelial-like cells, vasculogenic vessel growth, and vessel co-option, may emerge, many of which respond poorly to VEGF-targeted therapies [3]

GSH may influence the viral infection by the (a) regulation of nuclear factor kappa B (NF-kappa B) activation of the infected cells (71), (b) interference of virus entry (72), and (c) inhibition of apoptosis and the release of active virus from the infected cells (73)

Metformin induces apoptosis and alters cellular responses to oxidative stress in ht29 colon cancer cells: preliminary findings

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