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Regulation of mitochondrial biogenesis and its intersection with inflammatory responses

New Trends Clin Neuropharmacol 1989;3(1):17-24

Low concentration of a mitochondrial uncoupler induces mild ROS production and PQQ extends the lifespan by increasing endogenous ROS levels 89

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A partial least-squares discriminant analysis showed distinct separation between these groups based on their metabolomes (Fig

It has been recently proposed that a significant number of ASD cases could be associated with various metabolic abnormalities, some of them identifiable only through untargeted metabolomic profiling, simultaneously opening additional space for therapeutic attempts ( Inborn Errors of Metabolism Clinical symptoms deriving from central nervous system (CNS) occur in more than 50% of patients with inborn errors of metabolism (IEM)