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To further understand these metabolic changes, pathway analysis was performed to know the biological implications of these differential metabolites

HGF largely originate from mesenchymal cells which acts in a paracrine manner on epithelial cells that express the c-MET receptor

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Crucially, Yangs study further verified that, attributable to RVG29 modification, the targeted nanocarrier (Cur@GAR NPs) exhibited superior improvement in neurobehavioral function compared to unmodified nanoparticles (Cur@Gel NPs) in cerebral ischemia models

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