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This process is exacerbated by smoking, pollution, exposure to UV or ionizing radiation, eating fried foods or those cooked at high temperatures, as well as engaging in high-intensity exercise (12)

Vitamin C recycles oxidised glutathione back to active form

GSH depletion is also strongly associated with aging

Adolescent offspring exposed to combined prenatal THC and chronic stress exhibited impairments in anxiety-related and motivated behaviors across sexes

(PubMed) Annweiler C, Schott AM, Allali G, et al

By triggering ferroptosis, -elemene improves the susceptibility of KRAS-mutant CRC cells to cetuximab, suggesting a potential therapeutic option for RAS-mutated CRC patients