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A.NodzenskiE.et al (1997)

Diabetes-Induced autophagy dysregulation engenders testicular impairment via oxidative stress

In this review, we will systematically summarize the recent progress in amino acid metabolism in the context of cancer and the tumor microenvironment, describe their interconnection or indispensable role in cancer growth, epigenetic modification, cancer immunity, and ferroptosis, and discuss the potential therapeutic applications for targeting amino acid metabolism

This example suggests that modifications to regulatory genes, including those not yet identified, may augment T-cell proliferation and inflammation observed in psoriasis