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Show that mutating the TDP-43 NLS for a PY-NLS from HNRNPA1 rescues the loss of SUMOylation phenotype, highlighting that it is the nuclear localization itself and not the lysines within the TDP-43 NLS that is mediating this phenotype

ROS overabundance in cell can have serious nefarious consequences, disrupting macromolecules and altering multiple biological pathways, ultimately leading to malignant cell transformation and cancer development

When doses are withdrawn use aseptic technique in order to avoid contamination and preserver solution integrity

observed bone pain and hematoma in 80% of patients treated with BMMCs, while 20% of those receiving FSC therapy developed scalp dermatitis [81]

Boosters are additional doses of the same vaccine needed to maintain immunity if it decreases over time

doi: 10.1152/ajprenal.00125.2016 107 LevineBYuanJ