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As interest in semaglutide fat loss and similar therapies grows, understanding how these peptides function and their clinical efficacy is crucial for healthcare professionals and individuals seeking targeted fat reduction solutions

Vitamin B12 status upon short-term intervention with a vegan diet-a randomized controlled trial in healthy participants

Ethics declarations Ethics approval and consent to participate The study protocol and informed consent were approved by the Institutional Ethics Committee of: Shanghai Ninth Peoples Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (SH9H-2024-T69-1) Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine (2024K16) The First Affiliated Hospital of Xinjiang Medical University (K202501-03) Zhejiang University School of Medicine (2025-031) Huashan Hospital Affiliated to Fudan University (2025-701) Before signing the consent form, participants will be informed about interventions and potential AEs

In some cases, high-dose daily oral B12 supplements (typically 1000 g daily) can also be used as an effective alternative or addition for maintenance therapy [9] [10]

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